|Project status: running|
|Work distributed:||61 %|
Today, protein sequence comparison is one of the most powerful tools in computational biology. It allows characterizing protein sequences based on the information that is preserved in evolution. Many computational methods in biology and medicine are based on protein sequence analysis, e.g. to predict the function and structure of genes and proteins. SIMAP facilitates these methods by providing pre-calculated protein similarities and protein domains. Read more...
SIMAP contains about all currently published protein sequences and is continuously updated. In BOINCSIMAP, we calculate every month the similarities and domains of newly imported proteins, in order to keep the SIMAP database up-to-date. Protein similarities are computed using the FASTA algorithm which provides optimal speed and higher sensitivity compared to the popular BLAST. Protein domains are calculated using the InterPro methods and databases. Read more...
The SIMAP database is a huge bioinformatic resource that is used by scientists for very different purposes. Individual researchers use the SIMAP database via the public Web portal, e.g. to investigate the evolution and function of individual proteins. Furthermore, many bioinformatics projects access SIMAP directly via the public Webservice or large-scale download facilities. Your support for BOINCSIMAP keeps the SIMAP database running.
BOINC lets you contribute unused computing power on your home PC to projects doing research in many scientific areas. You can contribute to a single project (like BOINCSIMAP), or to any combination of them. It's easy to participate in a BOINC project: download and install BOINC. You will be asked to select a project and enter your email address and a password. That's it! Read more...
New publication about SIMAP introduces new interfaces and increased coverage. SIMAP covers all major public protein databases as well as many consistently re-annotated metagenomes from different repositories. SIMAP currently contains more than 163 million proteins corresponding to about 70 million non-redundant sequences. The calculation of all-against-all sequence similarities and functional annotations would not be possible without the BOINCSIMAP public grid. Novel tools for interactive extraction of protein similarity networks have recently been added to SIMAP. New Web-Service interfaces enhance the connectivity of SIMAP. These improvements were published recently in the Database issue of Nucleic Acids Research.
23 Nov 2013, 15:25:05 UTC
Server software upgraded
30 Aug 2013, 13:23:55 UTC
Workunits for September upcoming
28 Aug 2013, 15:13:17 UTC
Server upgrades finished; old URL disabled